Amsterdam Scientific Instruments B.V. appoints Thorbjoern Schoenbeck as Chief Executive Officer

AMSTERDAM, The Netherlands – Amsterdam Scientific Instruments B.V. (“ASI”) today announced that Amsterdam Scientific Instruments B.V. has appointed Thorbjoern Schoenbeck as CEO and chairman of the executive board.

In addition, Hans Brouwer and Steven Tan, who managed ASI since 2017, will join the executive board. The new leadership appointments are effective immediately and will enable ASI to execute its ambitious corporate development strategy focused on continuous innovation and persistent growth.

“We are fortunate to have someone of Thorbjoern’s caliber and experience joining ASI,” said Hans Brouwer. “After having developed ASI from a small academic startup to a fast-growing company with a robust organization, top-tier customer base and mature product portfolio, we need renewed leadership to successfully bring the company to the next phase of development and growth. Thorbjoern has a strong background in high-tech and a proven track record commercializing advanced instrumentation. He is a strong communicator who understands our customers, both academic and industrial. Furthermore, having served in various sales leadership roles at Malvern Panalytical for the past 14 years, Thorbjoern has a solid understanding of our products and markets.”

Thorbjoern Schoenbeck said, “I am honored and excited to lead ASI. I believe ASI has a great team, a unique innovation power and a wonderful portfolio of products that will empower researchers around the world to push the frontiers of life sciences and physics and to force breakthrough innovations that will change the world.”

Speaking on behalf of Value Creation Capital, one of ASI’s investors, Willem van den Berg said, “We very much appreciate Steven Tan and Hans Brouwer for developing and driving ASI to its current successful position and for having the awareness and insight that new leadership and governance is required in anticipation of the next phase of the development of ASI. We believe that Thorbjoern has the right expertise, communication skills and leadership abilities to inspire the team and deliver on ASI’s ambitions.”


TPX3CAM with Cricket image intensifier

ASI TPX3CAM with Photonis Cricket image intensifier.

AMSTERDAM, The NetherlandsPhotonis, expert manufacturer of electro-optic components and Amsterdam Scientific Instruments (ASI) have agreed to an exciting joint venture.

Photonis is a global innovator, developer, and supplier of photo sensor technologies. Photonis has agreed to supply ASI with highly optimized image intensifier for ASI’s ultra-fast optical imaging camera TPX3CAM.

“The TPX3Cam combined with our Photonis Cricket offers single photon imaging with high spatial and time resolution”, says Evert van Gelder, Global director of Sales and Business development. Its fast timing capabilities make it equally suitable for time-of-flight imaging of ions, electrons or neutrons. A truly versatile product.”

The joint efforts of Photonis and ASI is expected to improve the affordability and accessibility of high-quality single photon detectors. The collaboration will benefit researchers from all over the world who wish to image single photons with time sensitive data. TPX3CAM offers time resolution of 1.6 ns, continuous data readout, and can be used as stand-alone detector, or be easily integrated in table-top lab setups or free-electron-laser environments.

To find out more about TPX3CAM please visit

Happy Holidays from ASI

Season’s Greetings from ASI

Season's greetigs from ASI
As we wind down for 2020, our team at ASI would like to thank you for your continued trust in us. Despite the uncertainties and challenges 2020 has brought, ASI was able to grow and make strides towards our mission: to progress the pace and scope of scientific research by enabling more sensitive and accurate measurement of high-energy particles.

In 2021, we look forward to providing you with even more innovative imaging solutions to help you make breakthrough discoveries. Be sure to follow us on LinkedIn as ASI has many exciting things planned for 2021 – and we know you won’t want to miss out!

We wish you a safe & happy holiday! Cheers!

Colleagues working from home

ASI Encourages Colleagues to Work From Home

Due to the rapid increase in the number of COVID-19 cases in the Netherlands, the Dutch government has advised its people to limit any unnecessary travel and contact for the foreseeable future.

At ASI, the health and well-being of our team are of upmost importance. That’s why, we encourage everyone to work from home as much as possible during these uncertain times.

Stay safe everyone~

Colleagues working from home

Although physically far, we still find time for gezelligheid*! *cosy & fun times in Dutch

Hybrid Pixel Technology Provides Data that You Can Rely On: An Indispensible Advancement for TEMs

In this interview, AZoM talks to Yemliha Bilal Kalyoncu, Application Engineer at Amsterdam Scientific Instruments about how an indispensable advancement for TEMs is provided by hybrid pixel technology.


Can you give a brief overview of Amsterdam Scientific Instruments, and what sets you apart from other members of your industry?

Amsterdam Scientific Instruments is an innovative company dedicated to producing and marketing the most advanced detector systems for scientific and OEM customers that want the next generation detector technology. It has emerged from NIKHEF (National Dutch Institute for subatomic physics) Institute of the University of Amsterdam as a result of joint scientific efforts with CERN. The hybrid pixel technology was born from this collaboration and quickly found applications in various fields from particle physics to X-ray imaging in synchrotrons and to electron microscopy applications.

This technology is based on sophisticated read-out ASICs, called Medipix/Timepix, where high-resolution timing and spectral/intensity information of particles can be obtained. While CERN produces these ASICs, ASI has pioneered in utilizing these sensors to manufacture a single electron sensitive electron detector for transmission electron microscopes: The CheeTah.

ASI is a global player in the X-ray imaging industry with the LynX series and produces highly sensitive direct electron detectors for transmission electron microscopes. Besides, we also manufacture a patented, single-photon counting detector: TPX3CAM. A unique camera that opens its own field for time-resolved measurements.

What sets us apart is the benefits of hybrid pixel technology that we offer with every product: noiseless data, high-speed read-out, and high dynamic range are only three examples among many.

The Cheetah Detector
The CheeTah Detector

Can you please elaborate more to our readers on the benefits of a hybrid pixel/direct electron detector?

For each application, the benefit would be different. But the bottom line is data that you can 100% rely on and that allows you to observe effects that were not seen before. The detector eliminates noise at the sensor level and results in unprecedented high signal to noise ratios. If we would like to give some numbers, the CheeTah M3 allows event counting with a 24bit dynamic range for intensity measurements, and on the other hand, the CheeTah T3 records timing of impinging electrons with 1.56 ns time resolution. Moreover, the continuous read-write mode and novel read-out schemes grant dead-time free recording with speeds of 2000 fps with 12 bits counter-depth, without sacrificing resolution.

It depends on each specific experiment, in which one of these features should be exploited for the best performance. To give few examples: high dynamic range is necessary for 4D-STEM experiments in material science, high SNR is essential for low dose applications on beam sensitive samples, and 1.56ns time resolution is good for ultrafast TEMs and in-situ measurements. We also now introduce a 1megapixel detector for life-sciences where high resolution is necessary for resolving structures with large unit-cells.

How does the CheeTah detector compare to a conventional CCD or CMOS camera?

In CheeTah detector, each pixel is actually an individual detector with its own electronics for counting electrons and processing the signal. Upon that, each pixel has a separate channel for read-out. This architecture allows a single electron sensitivity with zero noise and high-speed read-out. That is very different than the working principle of standard CCD and CMOS detectors, where pixels share electronic circuitry and require binning for faster operation. Moreover, noise, radiation damage, saturated pixels are intrinsic problems these conventional detectors have.

Can the CheeTah detector boost the power of TEM? If so, how?

Transmission Electron Microscopes (TEM) have been developed more advanced recently and they can now dive deeper in structures to allow much more precise information. However, the challenge arises in the accurate capture and the visualization of this precise information.

The CheeTah stands as an excellent solution for the microscopy society, not only for basic electron diffraction experiments but also to answer the needs of recent complementary TEM techniques such as Precession Electron Diffraction, 4D STEM, microED and EELS, where standard CCD and CMOS detectors lack the competence to capture the information these methods can give.

Are there any additional features of the CheeTah? 

An additional feature is an application-specific interface (API) that allows integration of the detector in any system for remote control. This is a language-independent interface where users can simply implement in their own algorithms for synchronized frame acquisition.

Mechanics are also important for customers because the ports on the microscope may be limited to place a detector. We manufacture bottom static cameras and retractable versions on the 35mm side port, but we also make customized designs for clients’ specific needs.

Who will benefit most from the EM-CheeTah?

The CheeTah M3 is superior in diffraction experiments. Material scientists benefit the CheeTah’s high dynamic range and speed for example in 4D-STEM experiments. Structural biologists and crystallographers exploit the high SNR such that they can work on low doses but still obtain sufficient intensity. A new era is opening up in materials science such as EELS where CCD detectors are replaced with direct electron detectors. On the other hand, CheeTah T3 is the detector of choice for ultrafast, time-resolved, or in-situ measurements.

Cheetah 1800 installation
CheeTah M3 installation

Do you have any examples where the CheeTah has demonstrated its abilities?

Yes, there are many publications in top journals where the data are recorded with the CheeTah Detector. Protein structure determination is a good example; Prof. J.P.Abrahams (PSI – Switzerland) has stated years ago that hybrid pixel detectors boost the power of electron microscopes and allowed him to solve protein structures as small as 100nm.  And there are more unknown structures out there to be discovered with the CheeTah detector.

Another example and user testimonial in material sciences are from Prof. Xiaodong Zou (Stockholm University – Sweden). She makes use of the CheeTah detector for ab initio structure determination of crystals that are too small for X-ray diffraction. She employs continuous rotation electron diffraction on those crystals and obtains data with improved quality and shortens the data collection time.

What’s next for Amsterdam Scientific Instruments?

Our vision is to expand our field of applications. Materials science and Life sciences are fields with challenges. We keep the new applications always in our radar and collaborate with key scientists to advance the CheeTah detector for the best performance in these applications. This year is very exciting for us with the introduction of the 1 Megapixel detector, which makes us the global leader with ‘gapless’ megapixel hybrid pixel technology for MicroED.

The next step for Amsterdam Scientific Instruments is to realize our vision as we have been enabling since the beginning: to make the invisible visible.